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1 edition of Toxicology and Carcinogenesis Studies of Naphthalene (Cas No. 91-20-3) in B6C3F1 Mice, Technical Report Series, No. 410, U.S. Dept. of Health and Human Services, 1995. found in the catalog.

Toxicology and Carcinogenesis Studies of Naphthalene (Cas No. 91-20-3) in B6C3F1 Mice, Technical Report Series, No. 410, U.S. Dept. of Health and Human Services, 1995.

Toxicology and Carcinogenesis Studies of Naphthalene (Cas No. 91-20-3) in B6C3F1 Mice, Technical Report Series, No. 410, U.S. Dept. of Health and Human Services, 1995.

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Published .
Written in English


Edition Notes

ContributionsNational Cancer Institute (U.S.)
ID Numbers
Open LibraryOL17698275M

naphthalene administered by gavage to Sprague-Dawley rats on gestational days 6 through Research Triangle Institute. Research Triangle Park, NC: National Toxicology Program. NTP. Toxicology & Carcinogenesis Studies of Naphthalene in B6C3F1 Mice. Technical Report Series No. NIH Publication No. Shopp GM, White KL, and File Size: 1MB. Toxicology and carcinogenesis studies of a nondecolorized [corrected] whole leaf extract of Aloe barbadensis Miller (Aloe vera) in F/N rats and B6C3F1 mice (drinking water study). Boudreau MD, Beland FA, Nichols JA, Pogribna M. Erratum in Natl Toxicol Program Tech Rep Ser. Aug;()Cited by:

A Textbook of Modern Toxicology, Fourth Edition continues from prior editions with coverage of basic concepts in toxicology and expands its scope by adding chapters on molecular methods, bioinformatics and systems biology. Up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing /5(3). The clinical syndrome due to chlorinated naphthalene toxicity in cattle, sheep and goats was termed hyperkeratosis or X disease because of skin thickening due to hyperkeratosis. The chlorinated naphthalenes caused squamous metaplasia of the vagina, cervix and uterus, as well as Gartner’s ducts leading to cystic enlargement (see Figure ).

  The toxicologic and carcinogenic potential of naphthalene was studied by exposing groups of male and female B6C3F 1 mice to atmospheres containing 0 (75 mice per sex), 70 ppm (75 mice per sex), or 30 ppm ( mice per sex) of the chemical for 6 h daily, 5 dayslwk for wk. The final mean body weights of mice exposed to naphthalene were similar to those of the by: His studies have included the hepatobiliary disposition of xenobiotics, the toxicity of cadmium, the hepatotoxicity of chemicals, and mechanisms of chemical-induced thyroid tumors. Dr. Klaassen is editor of Casarett and Doull’s Toxicology: The Basic Science of Poisons, considered the premier textbook in the field. He has twice been named a.


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Toxicology and Carcinogenesis Studies of Naphthalene (Cas No. 91-20-3) in B6C3F1 Mice, Technical Report Series, No. 410, U.S. Dept. of Health and Human Services, 1995 Download PDF EPUB FB2

To control lice on livestock and poultry. Naphthalene was selected for study by the National Toxicology Program because previous inhalation studies with naphthalene in mice were positive and existing studies in rats were either considered inadequate or were conducted via File Size: 8MB.

studies of naphthalene (casno. ) in b6c3fl mice (inhalation studies) national toxicology program p.o. box researchtrianglepark,nc File Size: 8MB.

Genetic toxicology studies were conducted in Salmonella typhimurium and cultured Chinese hamster ovary cells. 2-YEAR STUDY: Groups of 49 male and 49 female rats were exposed to naphthalene by inhalation at concentrations of 0, 10, 30, or 60 ppm for 6 hours plus T90 (12 minutes) per day, 5 days per week for weeks.

Genetic toxicology studies were conducted in Salmonella typhimurium and Chinese hamster ovary cells. 2-Year Studies: Groups of male and female mice were exposed to atmospheres containing 0 (75 mice per group), 10 (75 mice per group), or 30 ppm ( mice per group) : National Toxicology Program.

Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. ) in B6C3F1 Mice (Inhalation Studies). National Toxicology Program.

Naphthalene, a white, crystalline powder, is used as a moth repellent and in the manufacture of phthalic and anthranilic acids, naphthylamines, and synthetic resins.

NTP technical report on the toxicology and carcinogenesis studies of sodium fluoride (CAS no. ) in F [Anonymous.] on *FREE* shipping on qualifying offers.

NTP technical report on the toxicology and carcinogenesis studies of sodium fluoride (CAS no. ) in F rows    Long-term NTP toxicology and carcinogenicity studies in rodents are the. The five unpublished studies of naphthalene genotoxicity include three studies in vitro (two Ames bacterial assays and an in vitro unscheduled DNA synthesis assay) and two in vivo (mouse micronucleus and in vivo unscheduled DNA synthesis).

Naphthalene was inactive in all five studies, in agreement with reports in the published by:   (). Toxicology and carcinogenesis studies of dietary titanium dioxide‐coated mica in male and female Fischer rats.

Journal of Toxicology and Environmental Health: Vol. 28, No. 4, Cited by: In today's terms, toxicology is an applied science that is built on other medical sciences including physiology (the study of living organisms), biochemistry (the chemistry of living organisms), pathology (the study of diseases and their progression in the body), pharmacology (the study of drugs on living organisms), medicine (the science of diagnosing, treating, or preventing disease and.

Toxicology and Carcinogenesis Studies of Urethane, Ethanol, and Urethane/Ethanol in B6C3F1 Mice (Drinking Water Studies) [P.C. Chan] on *FREE* shipping on qualifying offers. A report on a 2-year drinking water study. The major source of human exposure to urethane (ethyl carbamate) is from fermented foods and beverages.

Urethane in combination with ethanol was nominated by the. Carcinogenicity is demonstrated by studies that are interpreted as showing no chemically related increases in malignant or benign neoplasms.

Inadequate Study. Carcinogenicit demonstrates that because of major ualitative or quan- titative limitations, the studies cannot %e interpreted as valid for showing eit. er the presence orFile Size: 8MB. Get this from a library. NTP technical report on the toxicology and carcinogenesis studies of naphthalene (CAS no.

) in B6C3F₁ mice (inhalation studies). [National Toxicology. National Toxicology Program (NTP, ). Toxicology and Carcinogenesis Studies of Naphthalene (CAS No.

) in B6C3F1 Mice (Inhalation Studies). Technical Report Series No. NIH Publication No. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Size: KB. Toxicology and carcinogenesis studies of naphthalene (CAS no.

) in B6C3F₁ mice (inhalation studies) Naphthalene (inhalation studies) Responsibility: National Toxicology Program. Toxicology and Carcinogenesis Studies of Stoddard Solvent IIC (CAS NO. ) in F/N Rats and B6C3F1 Mice (Inhalation Studies) [P.C.

Chan] on *FREE* shipping on qualifying offers. Toxicology and Carcinogenesis Studies of Stoddard Solvent IIC (CAS NO. ) in F/N Rats and B6C3F1 Mice (Inhalation Studies)Manufacturer: NCI.

NTP technical report on the toxicology and carcinogenesis studies of 2, 6-xylidine (2, 6-dimethylaniline) (CAS no. ) in Charles River CD rats (feed studies) (SuDoc HE /) [Mary Kornreich] on *FREE* shipping on qualifying offers.

TOXICOLOGY AND CARCINOGENESIS. STUDIES OF METHYL BROMIDE (CAS NO. ) IN B6C3F. MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box Research Triangle Park, NC March NTP TR NIH Publication No.

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National Institutes of. NTP,Draft NTP Technical Report on the Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. ) in F/N Rats (Inhalation Studies), U.S. Dept. Health and Human Services, Public Health Service, National Institutes of Health, Research Triangle Park, by: Cover title: Toxicology and carcinogenesis studies of naphthalene.

This banner text can have markup. malignant tumors among male rats exposed via inhalation to naphthalene by the National Toxicology Program (NTP, ).

The male rat was the most sensitive sex and species tested by NTP (; ) in the inhalation carcinogenesis studies of Size: KB.National Toxicology Program,Toxicology and Carcinogenesis Studies of Naphthalene (Cas No.

) in F/N Rats. U.S. Department of Health and Human Services, National Institutes of Health, Public Health Service, Bethesda, by:   The National Toxicology Program (NTP) more recently classified naphthalene as “Reasonably anticipated to be a human carcinogen” based on inadequate epidemiology studies but “sufficient evidence from studies in experimental animals” (NTP ).Cited by: